In upcoming posts, I plan to pursue two main themes. The first is a more comprehensive exploration of what determines eating behavior in humans, the neurobiology behind it, and the real world implications of this research. The reward and palatability value of food are major factors, but there are others, and I've spent enough time focusing on them for the time being. Also, the discussions revolving around food reward seem to be devolving into something that resembles team sports, and I've had my fill.
The second topic I'm going to touch on is human evolutionary history, including amazing recent insights from the field of human genetics. These findings have implications for the nutrition and health of modern humans.
I look forward to exploring these topics, and others, with all of you in the coming months.
Recent Media Appearances
Men's Health interviewed and quoted me in an article titled "Reprogram Your Metabolism", written by Lou Schuler. Part of the article was related to the food reward concept. I'm glad to see the idea gradually reaching the mainstream.
Boing Boing recently covered an article by Dr. Hisham Ziauddeen and colleagues in Nature Reviews Neuroscience that questioned the idea that common obesity represents food addiction-- an idea that I often encounter in my reading. Maggie Koerth-Baker asked me if I wanted to respond. I sent her a response explaining that I agree with the authors' conclusions and I also doubt obesity is food addiction per se, as I have explained in the past, although a subset of obese people can be addicted to food. I explained that the conclusions of the paper are consistent with the idea that food reward influences fat mass. You can find my explanation here.
Boing Boing recently covered an article by Dr. Hisham Ziauddeen and colleagues in Nature Reviews Neuroscience that questioned the idea that common obesity represents food addiction-- an idea that I often encounter in my reading. Maggie Koerth-Baker asked me if I wanted to respond. I sent her a response explaining that I agree with the authors' conclusions and I also doubt obesity is food addiction per se, as I have explained in the past, although a subset of obese people can be addicted to food. I explained that the conclusions of the paper are consistent with the idea that food reward influences fat mass. You can find my explanation here.
Food Reward: Approaching a Scientific Consensus
Review papers provide a bird's-eye view of a field from the perspective of experts. Recent review papers show that many obesity researchers are converging on a model for the development of obesity that includes excessive food reward*, in addition to other factors such as physical inactivity, behavioral traits, and alterations in the function of the hypothalamus (a key brain region for the regulation of body fatness). Take for example the four new review papers I posted recently by obesity and reward researchers:
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Xperia Neo L will be Sony's first ICS phone, but only for China?
Appearing on the company's Chinese website, we wouldn't expect a redux of the mostly 2011 hardware to go on a world tour anytime soon. Those buying will be treated to a 4-inch FWVGA (854 x 480) screen that's a smidge bigger than the original yet still carries a 1GHz worth of Snapdragon coupled to 512MB of RAM.
Unlike the archetype, though, the camera gets downgraded to a 5 megapixels in the rear while retaining the same VGA shooter in the front. Naturally there's no word on price or availability, but at least for diehard fanboys can have their ice cream and eat it too.
Speaking at AHS12
I'll be giving a 40 minute presentation at the Ancestral Health Symposium this summer titled "Digestive Health, Inflammation and the Metabolic Syndrome". Here's the abstract:
What determines this? Emerging research suggests that one factor is digestive health, including the bacterial ecosystem inside each person's digestive tract, and the integrity of the gut barrier. I'll review some of this research in my talk, and leave the audience with actionable information for maintaining gastrointestinal and metabolic health. Most of this information will not have been covered on this blog.
The Ancestral Health Symposium will be from August 9-12 at Harvard Law School in Boston, presented in conjunction with the Harvard Food Law society. Tickets are currently available-- get them before they sell out! Last year, they went fast.
See you there!
Excessive fat mass is an important contributor to the metabolic syndrome, but at the same level of body fatness, some people are metabolically normal while others are extremely impaired. Even among obese people, most of whom have the metabolic syndrome, about 20 percent are metabolically normal, with normal fasting insulin and insulin sensitivity, normal blood pressure, normal circulating inflammatory markers, and normal blood lipids.The “metabolic syndrome” is a cluster of health problems including abdominal obesity, insulin resistance, low-grade inflammation, high blood pressure and blood lipid abnormalities that currently affects one third of American adults. It is the quintessential modern metabolic disorder and a major risk factor for diabetes, heart disease and certain cancers. This talk will explore emerging links between diet, gut flora, digestive health and the development of the metabolic syndrome. The audience will learn about factors that may help maintain digestive and metabolic health for themselves and the next generation.
What determines this? Emerging research suggests that one factor is digestive health, including the bacterial ecosystem inside each person's digestive tract, and the integrity of the gut barrier. I'll review some of this research in my talk, and leave the audience with actionable information for maintaining gastrointestinal and metabolic health. Most of this information will not have been covered on this blog.
The Ancestral Health Symposium will be from August 9-12 at Harvard Law School in Boston, presented in conjunction with the Harvard Food Law society. Tickets are currently available-- get them before they sell out! Last year, they went fast.
See you there!
Qnexa, the Latest Obesity Drug
There are very few obesity drugs currently approved for use in the US-- not because effective drugs don't exist, but because the FDA has judged that the side effects of existing drugs are unacceptable.
Although ultimately I believe the most satisfying resolution to the obesity epidemic will not come from drugs, drugs offer us a window into the biological processes that underlie obesity and fat loss. Along those lines, here's a quote from a review paper on obesity drugs that I think is particularly enlightening (1):
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Although ultimately I believe the most satisfying resolution to the obesity epidemic will not come from drugs, drugs offer us a window into the biological processes that underlie obesity and fat loss. Along those lines, here's a quote from a review paper on obesity drugs that I think is particularly enlightening (1):
Read more »
Boing!
I just had a featured article published on Boing Boing, "Seduced by Food: Obesity and the Human Brain". Boing Boing is the most popular blog on the Internet, with over 5 million unique visitors per month, and it's also one of my favorite haunts, so it was really exciting for me to be invited to submit an article. For comparison, Whole Health Source had about 72,000 unique visitors last month (200,000+ hits).
The article is a concise review of the food reward concept, and how it relates to the current obesity epidemic. Concise compared to all the writing I've done on this blog, anyway. I put a lot of work into making the article cohesive and understandable for a somewhat general audience, and I think it's much more effective at explaining the concept than the scattered blog posts I've published here. I hope it will clear up some of the confusion about food reward. I don't know what's up with the image they decided to use at the top.
Many thanks to Mark Frauenfelder, Maggie Koerth-Baker, and Rob Beschizza for the opportunity to publish on Boing Boing, as well as their comments on the draft versions!
For those who have arrived at Whole Health Source for the first time via Boing Boing, welcome! Have a look around. The "labels" menu on the sidebar is a good place to start-- you can browse by topic.
The article is a concise review of the food reward concept, and how it relates to the current obesity epidemic. Concise compared to all the writing I've done on this blog, anyway. I put a lot of work into making the article cohesive and understandable for a somewhat general audience, and I think it's much more effective at explaining the concept than the scattered blog posts I've published here. I hope it will clear up some of the confusion about food reward. I don't know what's up with the image they decided to use at the top.
Many thanks to Mark Frauenfelder, Maggie Koerth-Baker, and Rob Beschizza for the opportunity to publish on Boing Boing, as well as their comments on the draft versions!
For those who have arrived at Whole Health Source for the first time via Boing Boing, welcome! Have a look around. The "labels" menu on the sidebar is a good place to start-- you can browse by topic.
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Justin Bieber: 18th Birthday
Celebrating his milestone birthday Thursday on The Ellen DeGeneres Show, Bieber is presented by his manager with none other than a Fisker Karma - the highly coveted, ultra-exclusive plug-in hybrid luxury sports sedan.
"You work really really hard," his manager, Scooter Braun, tells him. "I always yell at you, 'Don't get anything flashy!' You know, we're not about that. Be humble, be humble. And I kind of broke my own rule."
Braun adds: "We wanted to make sure, since you love cars, that when you're on the road you are always environmentally friendly. And we decided to get you a car that would make you stand out … I think you know where I'm going, and you're kind of freaking out right now. That's a Fisker Karma."
Bieber looks shocked as he walks over to the vehicle, the most-wanted car in the world. "That's for me?! That's crazy!" he says.
Leonardo DiCaprio got the very first Fisker Karma ever made, and Al Gore and Colin Powell were among the first people on the waiting list for one.
Bieber also has a gift for fans on Thursday, announcing that his new single, "Boyfriend," will be out March 26.
Taylor Kitsch wondered whether his John Carter director
The 30-year-old Canadian-born actor plays the eponymous leading role in the upcoming Andrew Stanton helmed science-fiction action film. John Carter is a legendary comic superhero, created by American author Edgar Rice Burroughs in 1912, who battles wars on Mars.
Throughout shooting, Taylor filmed extremely physical scenes under Andrew's direction.
The actor laughed about what a toll the hardcore sequences took on his body.
"There were many times when I personally thought that [Andrew] had a vendetta," he joked to Cover Media.
"But he made a great point when we were filming, I don't know whether that was to motivate or what, but it was 'The more we beat you up, the more you're going to be liked!'"
Taylor trained rigorously to take on the challenges of this role.
"To say the least, this was by far the most exhausting thing I've ever been a part of," he shared.
Taylor is aware of the great importance of his role. He is hopeful that his performance will satisfy both diehard comic book fans and general movie lovers.
"I think it's just being honest to the character," Taylor explained.
"It's funny, once I first got the role, you're in the mix for a while, and for months on end I was saying to myself if I got the role, I was going to get 'comic book big.' But then when I got the script and the role I wanted to get the happy medium between the escapism and also staying real. So I'm very happy with the happy medium we have."
John Carter is released in UK cinemas from March 9 2012.
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